See How Multiphysics Simulation Is Used in Research and Development

Engineers, researchers, and scientists across industries use multiphysics simulation to research and develop innovative product designs and processes. Find inspiration in technical papers and presentations they have presented at the COMSOL Conference. Browse the selection below or use the Quick Search tool to find a specific presentation or filter by application area.
View the COMSOL Conference 2018 Collection
Bioscience and Bioengineeringx

Aplicação de Elementos Finitos na Ortodontia

T. O. Bassani [1], T. Bassani [2], A. Andriguetto [1], F. Schneider [2],
[1] Instituto Latino Americano de Pesquisa e Ensino Odontológico - ILAPEO, Curitiba, PR, Brasil
[2] Universidade Tecnológica Federal do Paraná – UTFPR, Curitiba, PR, Brasil

O presente estudo visou a avaliação, por meio do método dos elementos finitos, das tensões geradas em um arco ortodôntico chamado de Arco de Retração Dupla Chave, também conhecido como DKL. Para isso foram modeladas as geometrias do arco DKL, dos bráquets e das coroas dentais, no ... Read More

Effect of Duty Cycle Variation on Acoustic Pressure Field Simulation in an Ultrasound Bioreactor

A. Rahimi [1], J. Crapps [1], N. Case [1]
[1] Biomedical Engineering, Saint Louis University, Saint Louis, MO, USA

Daily application of a low intensity pulsed ultrasound (LIPUS) regimen has been shown to have positive effects on bone fracture healing. Although LIPUS treatment can induce cellular responses supporting bone repair, the underlying mechanisms are not well understood. Further in vitro ... Read More

Modeling Interface Response in Cellular Adhesion

G. Megali[1], D. Pellicanò[1], M. Cacciola[1], F. Calarco[1], D. De Carlo[1], F. Laganà[1], and F.C. Morabito[1]

[1]DIMET Department, Faculty of Engineering, University “Mediterranea” of Reggio Calabria, Reggio Calabria, Italy

Constitutive properties of living cells are able to withstand physiological environment as well as mechanical stimuli occurring within and outside the body. We examined fluid flow and Neo-Hookean deformation related to the rolling effect. A mechanical model to describe the cellular ... Read More

Lowering of the Interstitial Fluid Pressure as a Result of Tissue Compliance Changes during High Intensity Focused Ultrasound Exposure: Insights from a Numerical Model

E. Sassaroli[1], B. O'Neill [1]
[1]The Methodist Hospital Research Institute, Houston, TX, USA

Interstitial fluid pressure (IFP) is elevated in tumors. Owing to this elevated IFP, the interstitial fluid velocity (IFV) is negligible throughout the tumor but significant near the tumor margin. Any therapeutic strategy that can lower IFP will improve drug convection within the tumor ... Read More

Electro Thermal Performance Prediction of Radio Frequency Ablation System for Efficient Cancer Treatment

C. Thiagarajan[1], V. Gnanasekar[2]
[1]ATOA Scientific Technologies Pvt Ltd, Whitefield, Bangalore, Karnataka, India.
[2]Perfint Healthcare Pvt. Ltd, T.Nagar, Chennai, India.

Cancer causes significant human deaths. Radiofrequency ablation is an encouraging procedure for cancer treatment. The objective is to demonstrate the multiphysics simulation methodology. This paper summarizes the problem , governing equations, methodology, assumptions, simulation results ... Read More

Push or Pull, How Does Silk Flow?

J. Sparkes [1],
[1] University of Sheffield, Sheffield, UK

Silk is one of the longest used and most recognizable textiles that we, as a society, use regularly. We see it as a luxury good, worn as an indicator of success and value. However, despite mankind having domesticated and farmed silkworms for millennia, we still know relatively little ... Read More

Control-Release Anesthetics to Enable an Integrated Anesthetic-MSC Therapeutic

T. Maguire [1,2], M. Davis [1], I. Marrero-Berrios [1], C. Zhu [1], C. Gaughan [2], J. Weinberg [3], D. Manchikalapati [3], J. SchianodiCola [3], R. S. Schloss [1], J. Yarmush [3], M. Yarmush [1],
[1] Rutgers University, New Brunswick, NJ, USA
[2] BeauRidge Pharmaceuticals, New York, NY, USA
[3] Department of Anesthesiology, New York Methodist Hospital, Brooklyn, NY, USA

Introduction: While general anesthetics control pain via consciousness regulation, local anesthetics (LAs) act by decreasing sensation in the area of administration by blocking nerve transmission to pain centers. Perioperative intra-articular administration of LAs is a commonly employed ... Read More

Drop Simulation of Disposable Elastomeric Pump Using COMSOL Multiphysics® Software

R. Kapuganti [1], S. Anbazhagan[1],
[1] HCL Technologies, Chennai, India.

Drop test simulation is one of the important tool used for the impact behaviour study of electronic components. It identifies the flaws in design. The reliability and performance of electronic consoles after the drop is a major concern. Devices are expected to continue functioning after ... Read More

Modeling of Nerve Stimulation Thresholds and Their Dependence on Electrical Impedance with COMSOL

P. Krastev[1], and B. Tracey[1]
[1]Neurometrix, Inc., Waltham, Massachusetts, USA

Nerve localization is important for applications in regional anesthesia. Localization is achieved by stimulating the nerve with an electric field produced by a current from a needle inserted into the body of the patient, close to the target nerve.  Modeling of the electric field in ... Read More

In Silico Evaluation of Local Hemodynamics Following Vena Cava Filter Deployment

J. Ferdous[1], M. Ghaly [2], V. B. Kolachalama [3], T. Shazly[1,4]
[1]Biomedical Engineering Program, University of South Carolina, Columbia, SC, USA
[2]Department of Biomedical Engineering, North Carolina State University, Raleigh, NC, USA
[3]Charles Stark Draper Laboratory, Cambridge, MA, USA
[4]Department of Mechanical Engineering, University of South Carolina, Columbia, SC, USA

Inferior vena cava (IVC) filters have become essential components in deep vein thrombosis treatment to prevent preventing pulmonary embolisms. Filter efficacy relies on maintaining IVC patency by preventing filter-induced thrombosis following clot capture. A computational model has been ... Read More