See How Multiphysics Simulation Is Used in Research and Development

Engineers, researchers, and scientists across industries use multiphysics simulation to research and develop innovative product designs and processes. Find inspiration in technical papers and presentations they have presented at the COMSOL Conference. Browse the selection below or use the Quick Search tool to find a specific presentation or filter by application area.
View the COMSOL Conference 2018 Collection
Bioscience and Bioengineeringx

Design and Optimization of Cholesterol Biosensor

N. M. Sundaram[1], M. Alagappan[1]
[1]PSG College of Technology Coimbatore, Tamil Nadu, India

Cholesterol is an essential lipid for human body. The desired total plasma cholesterol for an individual is less than 5.2 mM (200 mg/dL) and it poses a potential health threat when the level is greater than 6.2 mM (240 mg/dL) [1]. Excessive plasma cholesterol causes poor cardiovascular ... Read More

Inlay Fixed Partial Denture Framework 3-D Structural Integrity Validation Using COMSOL Multiphysics®

T.M.R. Alho[1]

[1]Department of Electrical Engineering and Automation, University of Vaasa, Vaasa, Finland

Manual manufacturing of inlay fixed partial denture frameworks by metal casting can take hours of dental practitioners work time. This paper introduces 3-D simulations of premanufactured inlay fixed partial denture framework assembled from laser cut sheet metal parts. The study gives a ... Read More

Solving Calcium Spatiotemporal Diffusion Using COMSOL Multiphysics® Software new

L. Garber[1,2], G. S. B. Williams[2], W. J. Lederer[2]
[1]Fischell Department of Bioengineering, University of Maryland, Baltimore, MD, USA
[2]Center for Biomedical Engineering & Technology, University of Maryland, Baltimore, MD, USA

This project involves a simplified biological problem that was used to test the potential of COMSOL Multiphysics® software for cardiac myocyte spatial modeling. We made several assumptions to simplify the biological complexity and to highlight the geometrical structures (i.e., lack of ... Read More

Blood Flow Patterns in a Patient Specific Right Coronary Artery with Multiple Stenoses new

B. Liu[1]
[1]Department of Mathematics, Monmouth University, West Long Branch, NJ, USA

Atherosclerotic lesions preferentially develop in certain regions like bifurcations, branches, and bends [1, 2]. A possible explanation for such a preferential localization of atherosclerosis is that the geometry of the vessel influences the blood flow pattern. It suggests that the ... Read More

Flow-induced Vibrations of the Uvula and its Implication on Snoring

J. Xi[1], Q. M. Mohamad[1], Y. E. Yuan[1], J. Rohlinger[1]
[1]Mechanical and Biomedical Engineering, Central Michigan University, Mount Pleasant, MI, USA

1. Flow-induced uvula deformation considerably altered the flow dynamics inside the nose. 2. For a weak soft palate, complete flow occlusion can occur (sleep apnea). 3. Vibration of the airway structures is crucial to better understand snoring generation mechanisms and breathing ... Read More

Microvascular Dysfunction in PAD Patients new

K. Cluff[1], H. Mehraein[1], B. Jayakumar[2]
[1]Department of Bioengineering, Wichita State University, Wichita, KS, USA
[2]Department of Industrial & Manufacturing Engineering, Wichita State University, Wichita, KS, USA

Background: Peripheral arterial disease (PAD) is characterized by atherosclerotic blockages of the arteries supplying the lower extremities, which cause a progressive accumulation of ischemic injury to the skeletal muscles of the lower limbs. Despite revascularization treatment ... Read More

FEM Analysis and Optimization of Electro-Stimulating Implants for Bone Regeneration and Prevention of Bacterial Infection

T. Bender [1], J. Ziebart [2], T. J. Dauben [1], B. Kreikemeyer [3], R. Bader [2]
[1] Institute of Medical Microbiology, Virology and Hygiene, Rostock University Medical Center, Rostock, Germany; Research Laboratory for Biomechanics and Implant Technology, Department of Orthopedics, Rostock University Medical Center, Rostock, Germany
[2] Research Laboratory for Biomechanics and Implant Technology, Department of Orthopedics, Rostock University Medical Center, Rostock, Germany
[3] Institute of Medical Microbiology, Virology and Hygiene, Rostock University Medical Center, Rostock, Germany

The aim of this study is to investigate the influence of electro-magnetic stimulation on bone regeneration and the effect on bacterial infection. Electro-magnetic stimulation is a promising technique and a powerful tool for the enhancement of bone regeneration. To optimize the amplitude ... Read More

Bayesian Estimation of Tumors in Breasts Using Microwave Imaging

A. Jeremic[1], E. Khosrowshahli[1]
[1]McMaster University, Hamilton, ON, Canada

Although mammography is extremely important diagnostic technique, it suffers from some limitations such as false negative and positive results, using ionizing radiation and patient’s discomfort. Microwave imaging has been recently proposed as an additional medical imaging technique ... Read More

Electro Thermal Performance Prediction of Radio Frequency Ablation System for Efficient Cancer Treatment

C. Thiagarajan[1], V. Gnanasekar[2]
[1]ATOA Scientific Technologies Pvt Ltd, Whitefield, Bangalore, Karnataka, India.
[2]Perfint Healthcare Pvt. Ltd, T.Nagar, Chennai, India.

Cancer causes significant human deaths. Radiofrequency ablation is an encouraging procedure for cancer treatment. The objective is to demonstrate the multiphysics simulation methodology. This paper summarizes the problem , governing equations, methodology, assumptions, simulation results ... Read More

Modeling Plant Morphodynamics in Predefined COMSOL Multiphysics® Interface

S. Nikolaev[1], A. Trubuil[2]
[1]Institute of cytology and genetics SB RAS, Novosibirsk, Russia
[2]Institut National de la Recherche Agronomique, Jouy-en-Josas, France

We used a predefined COMSOL Multiphysics® interface to imitate biological growth and shape change (morphodynamics). We found a set of parameters that supply observed morphodynamics for an Arabidopsis embryo during its transition from globular to heart stage. Read More