Image-Based Simulation of Electrical Impedance Techniques Applied on the Human Thorax for Cardio-Pulmonary Applications
F.K. Hermans, R.M. Heethaar, R.T. Cotton, and A. Harkara
VU University Medical Center, Amsterdam, The Netherlands
Simpleware Ltd., Exeter, United Kingdom
For medical diagnostic purposes there is an increasing need for non- (or minimal) invasive techniques to measure all kinds of parameters that can provide insight in the functioning of cells, organs or organ systems. Currently, Impedance Cardiography (ICG) is used for measurements of the heart and Electric Impedance Tomography (EIT) is used for investigating lung tissue condition. This paper ...
A. Gizzi, C. Cherubini, S. Migliori, and S. Filippi
Nonlinear Physics and Mathematical Modeling Lab, Engineering Faculty, University Campus Bio-Medico, Roma, Italy
International Center for Relativistic Astrophysics, University of Rome La Sapienza, Roma, Italy
Alberto Sordi Foundation, Research Institute on Aging, Roma, Italy
Postoperative or paralytic Ileus (PI) is a temporary aftermath of major abdominal surgeries. PI prevents the passage of food throughout the lumen leading to bloating, distension, emesis and pain. A plausible mathematical model for this phenomenology physiologically fine tuned including thermal variations, is presented here. Using COMSOL Multiphysics the existing intestinal ionic model have been ...
Optimizing Performance of Equipment for Thermostimulation of Muscle Tissue using COMSOL Multiphysics
J. Kocbach, K. Folgerø, L. Mohn, O. Brix
Christian Michelsen Research, Bergen, Norway
Luzmon Norway, Bergen, Norway
Michelsen Medical, Bergen, Norway
The design challenge for thermostimulation equipment is to get a combination of high electric field strength and high temperature within the muscle tissue without causing pain or skin burns. In the present work, COMSOL Multiphysics is used to simulate the temperature distribution and electric field distribution within body tissue for varying body composition and varying design parameters of the ...
A. González-Suárez, M. Trujillo, J. Koruth, A. D'Avila, E. Berjano
Biomedical Synergy, Electronic Engineering Department,Universitat Politècnica de Valencia, Valencia, Spain
Instituto Universitario de Matemática Pura y Aplicada, Universitat Politècnica de Valencia, Valencia, Spain
Helmsley Cardiac Electrophysiology Center, Mt SinaiMedicalCenter and School of Medicine, New York, NY, USA
Previous studies proposed using bipolar radiofrequency ablation across two catheters placed on opposing surfaces of the ventricular wall to create transmural lesions. 2D and 3D models were built and solved with COMSOL Multiphysics software. With these models, it was possible to study the temperature distribution and lesion geometry (Figure), to compare the potential of two ways of applying ...
Temperature Excursions at the Pulp-Dentin Junction during the Curing of Light-Activated Dental Restorations
M. Jakubinek[1,2], C. Neill, C. Felix, R. Price[2,3], M. White[1,2]
Departments of Chemistry and Physics, Dalhousie University, Halifax, NS, Canada
Institute for Research in Materials, Dalhousie University, Halifax, NS, Canada
Department of Dental Clinical Sciences, Dalhousie University, Halifax, NS, Canada
Heat produced during the curing of light-activated dental restorations could damage the dental pulp. Given the prevalence of composite restorations and the importance of avoiding injury to the pulp, efforts should be made to minimize the temperature increase that occurs at the pulp-dentin junction during light-curing. In this investigation we develop and evaluate a COMSOL Multiphysics FEM tooth ...
R. Said, R. Cotton, P. Young, A. Datta , M. Elwassif, and M. Bikson
Simpleware Ltd, Exeter, UK
Department of Biomedical Eng, The City College of New York, USA
Electrical stimulation of the brain involves the application of currents delivered through scalp electrodes to modulate brain activity, known as Transcranial Current Stimulation (TCS). A critical factor for TCS efficacy and safety is the “spatial focality” of induced neuronal modulation. Bikson and coauthors from the City College of New York have been investigating the impact of disc ...
D. Krapohl, S. Loeffler, A. Moser, and U.G.Hofmann
Institute for Signalprocessing, University of Luebeck, Lübeck, Germany
Institute for Neurology, University of Luebeck, Lübeck, Germany
Department of Information Technology and Media, Mid Sweden University, Sundsvall, Sweden
Deep Brain Stimulation (DBS) has been established as an effective treatment for Parkinson's disease and other movement disorders. The stimulation is currently administered using tetrode-macroelectrodes that target the Subthalamic Nucleus (STN). This often leads to side effects which bias the surrounding areas, e.g. the speech centre. Targeting a specific brain region can better be achieved with ...
M. Cartas-Ayala, R. Karnik
Massachusetts Institute of Technology, Cambridge, MA, USA
Characterization of particles has numerous applications in science and diagnostics. Recently, particle passage through constrained microchannels has been proposed to characterize particles based on their passage velocity. Nevertheless, there is no clear understanding of how the physics in this system interact. Here we quantify the effects of the flow around the particle by simulating the passage ...
R. Sikorski, B. Chapman, T. Merrill
Rowan University, Glassboro, NJ, USA
A CFD cardiac catheter model was developed to determine the potential for blood hemolysis during administration of local therapeutic hypothermia using a CoolGuide catheter. In vivo animal studies have shown that mild hypothermia may reduce reperfusion injury often associated with heart attack. The CoolGuide Catheter System (CCS) delivers rapid local cooling through a cardiac catheter, reducing ...
R. Santoprete, B. Querleux
L'Oréal, Paris, France
To better quantify the impact of the morphological and mechanical properties of the main constituents of the stratum corneum (SC, the outermost layer of the skin) on its overall mechanical behavior, we developed a biomechanical model of the SC at a cellular scale, based on in vitro morphological and mechanical data. The sensitivity analysis quantified the relative impact of the mechanical and ...