E. M. Fontes
Catella Generics AB
Computational mathematical modeling has allowed scientists and engineers to perform better, faster, and more economical virtual experiments. Through mathematical modeling, an application expert can simulate performance characteristics during different operating conditions and thereby accelerate the pace of understanding new electrochemical system in relation to specific application ...
G. Shafirstein1, E. D. Bearden2, and W. Bäumler3
1 Department of Otolaryngology, Arkansas Children’s’ Hospital and University of Arkansas for Medical Sciences, Little Rock, AR, USA
2 Department of Information Technology, University of Arkansas for Medical Sciences, Little Rock, AR, USA
3Department of Dermatology, University of Regensburg, Regensburg, Germany.
Laser treatment of cutaneous vascular malformations such as port-wine stain (PWS) is a well accepted modality. However, there is still ambiguity regarding the optimal laser parameters to achieve maximum efficacy. In lack of animal models that mimic PWS, mathematical modeling is the primary tool to identify optimal laser settings. COMSOL was used to solve the light and heat diffusion equations ...
Department of Biomedical Engineering, University of Florida, Gainesville, FL, USA
We are developing approximations of electrically anisotropic materials for use in novel imaging methods. Our modeling work in COMSOL comprises comparisons of anisotropic and layered models in terms of electrical conductivities measured using different strategies. We tested solution stability in one anisotropic case by varying mesh anisotropy. In our case, good approximations to the true ...
R. Sadleir, A. Minhas, and E.J. Woo
University of Florida, Gainesville, FL, USA
Kyung Hee University, Seoul, Republic of Korea
In an earlier work we developed a finite element bidomain model of an aplysia abdominal ganglion in order to estimate the sensitivity of this contrast mechanism to changes in cell membrane conductance occurring during a gill-withdrawal reflex. We used our model to determine both current density and magnetic potential distributions within a sample chamber containing an isolated ganglion when it ...
J.L. Smart, and M. Kaliszan
University of Kentucky, Paducah, KY, USA
Medical University of Gdansk, Gdansk, Poland
COMSOL Multiphysics® 4.0 was used to study conductive and convective heat transfer from the human eyeball to the surrounding air. Postmortem temperature decay curves were collected in eyeballs of numerous human corpses. Of course, these curves represent only a portion of the complete temperature decay curve, since the pathologist is able to start collecting temperature data only after some ...
Simulation of a Magnetic Induction Method for Determining Passive Electrical Property Changes of Human Trunk Due to Vital Activities
H. Mahdavi, J. Rosell Ferrer
Universitat Politècnica de Catalunya, Barcelona, Spain
The human body consists of many different types of tissues each with specific passive electrical properties. Vital activities lead to a characteristic change of these properties and geometrical changes. Magnetic induction is a non-contact method which can be used to determine these changes. The method is based on the creation of a primary magnetic field that will produce eddy currents in the ...
P. Silva, J.A. Ferreira, P. de Oliveira
Coimbra Institute of Engineering, CMUC, Coimbra, Portugal
Department of Mathematics University of Coimbra, CMUC, Coimbra, Portugal
The aim of the poster is to present a coupled 2D mathematical model to predict the evolution of drug concentration - in the cornea and in the anterior chamber of the eye - when therapeutic lenses are used (Figure 1). The mathematical model takes into account (i) diffusion processes in several compartments of the eye (therapeutic lens, cornea and anterior chamber); (ii) metabolic consuming ...
J. Jimenez-Lozano, P. Vacas-Jacques, W. Franco
Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
Radiofrequency (RF) technology offers unique advantages for noninvasive selective heating of relatively large volumes of tissue. In this work, we present a mathematical model for selective non-invasive, non-ablative RF heating of cutaneous and subcutaneous tissue (with detailed fiber septa structures) including their thermo-elastic response. Our analysis shows that the fiber septa architecture ...
K. Cluff, H. Mehraein, B. Jayakumar
Department of Bioengineering, Wichita State University, Wichita, KS, USA
Department of Industrial & Manufacturing Engineering, Wichita State University, Wichita, KS, USA
Background: Peripheral arterial disease (PAD) is characterized by atherosclerotic blockages of the arteries supplying the lower extremities, which cause a progressive accumulation of ischemic injury to the skeletal muscles of the lower limbs. Despite revascularization treatment intervention some PAD patients require follow up secondary treatment due to a continued decline in limb function, ...
Hemodynamic Therapy of Middle Cerebral Artery Vasospasm Guided by a Multiphase Model of Oxygen Transport
S. Conrad[1,2], P. Chittiboina, and B. Guthikonda
Department of Bioinformatics and Computational Biology, Louisiana State University Health Sciences Center, Shreveport, LA, USA
Department of Biomedical Engineering, Louisiana Tech University, Ruston, LA, USA
Department of Neurosurgery, Louisiana State University Health Sciences Center, Shreveport, LA, USA
Cerebral vasospasm is a complication of subarachnoid hemorrhage and other neurosurgical emergencies that reduce blood flow to the brain. Part of the approach to management of vasospasm is to improve flow through the stenotic areas by reducing by decreasing blood viscosity and enhancing flow through the stenosis. To examine the interaction of these factors, we applied computational fluid dynamics ...