R. Sisto, L. Cerini, D. Mambro, A. Moleti, F. Sanjust
INAIL Research, Monteporzio Catone, Italy
Università di Roma, Tor Vergata, Italy
The otoacoustic emissions (OAEs) are acoustic signals emitted by the inner ear as a consequence of the activity of a nonlinear feedback mechanism capable of amplifying the signal near to the hearing threshold level. The otoacoustic emissions can be used as an acoustic imaging of the cochlear functionality. They are used in clinics for screening purposes but due to the extreme variability between ...
A. Avanzini, D. Battini, M. Berardi
Università degli Studi di Brescia, Brescia, Italy
The complex behavior of biological prosthetic heart valves was simulated. A multiphysics computational approach was adopted using different modules of COMSOL Multiphysics: the LiveLink(TM) interface was used to exchange the valve geometry with CAD, Structural Mechanics Module to set loads, boundary conditions and implement anisotropic hyper-elastic constitutive laws for leaflet tissue, PDE to ...
A Simplified Numerical Model for Simulating Sliding Door and Surgical Staff Movement in an Operating Theater
Dipartimento di Energetica, Università di Firenze, Firenze, Italy
This paper deals with a numerical investigation on sliding door and people moving effects on the indoor climate of a standard ISO5 class OT with an ultraclean air filter system and a total ceiling unidirectional diffuser. A simple method to analyze the effects on the OT climate by different sliding door conditions combined with crossing persons and persons with a stretcher crossing is provided. ...
D. Iber, J. Vollmer, D. Menshykau
Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland
Most models of biological pattern formation are simulated on continuous domains even though cells are discrete objects that provide internal boundaries to the diffusion of regulatory components. In our previous papers on simulating organogenesis in COMSOL Multiphysics® (Germann et al COMSOL Multiphysics® Conf Procedings 2011; Menshykau and Iber, COMSOL Multiphysics® Conf Proceedings 2012) we ...
An Assessment of the Suitability of the Body and Adult Head Coils for Transmission during Paediatric Magnetic Resonance Imaging
G.R. Cook, M.J. Graves, F.J. Robb, D.J. Lomas
Department of Radiology, University of Cambridge, Cambridge, United Kingdom
General Electric Healthcare Coils, Aurora, Ohio, USA
MRI offers many advantages over other modalities and its lack of ionizing radiation is important for children, but can be limited by the radio-frequency (RF) coils available. This work calculates Specific Absorption Rate (SAR) and homogeneity of the RF transmit field (B1+) when imaging infants in adult coils. Two birdcage-type coils were loaded by a tissue model and their B1+ homogeneities ...
O. Henao, V. Gómez, I. De la Pava, J. Sánchez
Grupo Fisiología Celular y Aplicada, Universidad Tecnológica de Pereira, Pereira, Risaralda, Colombia
Electroporation is an increase of the cell membrane permeability due to the formation of aqueous pores in it when the cell is under the influence of an intense electric field . The formation of such pores in the membrane can be used to enhance the uptake of chemotherapeutic drugs into the cell in a cancer treatment known as electrochemotherapy . In some cases the direct experimental ...
Hemodynamic Therapy of Middle Cerebral Artery Vasospasm Guided by a Multiphase Model of Oxygen Transport
S. Conrad[1,2], P. Chittiboina, and B. Guthikonda
Department of Bioinformatics and Computational Biology, Louisiana State University Health Sciences Center, Shreveport, LA, USA
Department of Biomedical Engineering, Louisiana Tech University, Ruston, LA, USA
Department of Neurosurgery, Louisiana State University Health Sciences Center, Shreveport, LA, USA
Cerebral vasospasm is a complication of subarachnoid hemorrhage and other neurosurgical emergencies that reduce blood flow to the brain. Part of the approach to management of vasospasm is to improve flow through the stenotic areas by reducing by decreasing blood viscosity and enhancing flow through the stenosis. To examine the interaction of these factors, we applied computational fluid dynamics ...
J.L. Smart, and M. Kaliszan
University of Kentucky, Paducah, KY, USA
Medical University of Gdansk, Gdansk, Poland
COMSOL Multiphysics® 4.0 was used to study conductive and convective heat transfer from the human eyeball to the surrounding air. Postmortem temperature decay curves were collected in eyeballs of numerous human corpses. Of course, these curves represent only a portion of the complete temperature decay curve, since the pathologist is able to start collecting temperature data only after some ...
Numerical Investigation of a Time-dependent Magnetic Actuation Technique for Tagging Biomolecules with Magnetic Nanoparticles in a Microfluidic System
A. Munir, J. Wang, Z. Zhu, and H.S. Zhou
Worcester Polytechnic Institute, Worcester, MA, USA
The magnetic body forces that act on mono-dispersed magnetic nanoparticles (MNPs) tagged biomolecules in a microfluidic system can be efficiently used in various applications that involve separation and detection including DNA and protein analysis, bio-defense, drug delivery, and pharmaceutical development. In this work, we report an FEM model to demonstrate a novel method of tagging biomolecules ...
A. Jeremic, and A. Atalla
McMaster University, Hamilton, ON, Canada
In this paper, we develop a mathematical model to simulate the movement of bacteria into and within a capillary segment. Also, we model the transportation through capillary walls by means of anisotropic diffusivity that depends on the pressure difference across the capillary walls. By solving the model using COMSOL, it was possible to predict the concentration of bacteria at points within the ...